ebdbNet: User Manual
نویسنده
چکیده
Gene regulatory networks consist of interactions among genes, transcription factors, proteins, and other cellular substances, and are generally thought to play an important role in many cellular functions. The ebdbNet package implements the Empirical Bayes Dynamic Bayesian Network (EBDBN) method (Rau et al., 2010), which estimates the posterior distributions of network parameters. The method also has the ability to infer gene regulatory networks from time-course data while simultaneously offering the flexibility to incorporate hidden states and/or driving inputs.
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